Statistics Applied to Clinical Trials

Preface. Foreword. 1. Hypotheses, Data, Stratification. 2. The analysis of efficacy data of drug trials. 3. The analysis of safety data of drug trials. 4. Equivalence testing. 5. Statistical power and sample size. 6. Interim analysis. 7. Multiple statistical inferences. 8. Principles of linear regression. 9. Subgroup analysis multiple linear regression: confounding, interaction, synergism. 10. Curvilinear regression. 11. Meta-analysis. 12. Crossover studies with continuous variables: power analysis. 13. Crossover studies with binary responses. 14. Post-hoc analysis in clinical trials, a case for logistic regression analysis. 15. quality-of-life assessment in clinical trials. 16. Statistics for the analysis of genetic data. 17. Relationship among statistical distributions. 18. Statistics is not "bloodless" algebra. Appendix. Index.