Butyrylcholinesterase : Its Function and Inhibitors

Two types of cholinesterases (ChEs) are found in the mammalian brain: acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE).

They are products of two different genes and exhibit different localizations and kinetic properties.

Until recently, the function of BuChE and its role in the regulation of acetylcholine levels in the central nervous system have been largely unknown.

There is now evidence that BuChE plays a vital role in the brain cholinergic system, and that it may have a key role in the development of Alzheimer's disease.

Butyrylcholinesterase: Its Function and Inhibitors is for neurologists, psychiatrists, geriatricians and neuroscientists who want a full profile of BuChE.