The gene: an intimate history

Spanning the globe and several centuries,The Geneis the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function.

The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856 where Gregor Mendel stumbles on the idea of a 'unit of heredity'. It intersects with Darwin's theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. Above all, it is a story driven by human ingenuity and obsessive minds - from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.

This is an epic, moving history of a scientific idea coming to life by the author ofThe Emperor of All Maladies. But woven throughThe Gene, like a red line, is also an intimate history - the story of Mukherjee's own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to "read" and "write" the human genome - unleashing the potential to change the fates and identities of our children.

Majestic in its ambition, and unflinching in its honesty,The Genegives us a definitive account of the fundamental unit of heredity - and a vision of both humanity's past and future.