C-Myc in B-cell Neoplasia : 14th Workshop on Mechanisms in B-cell Neoplasia

This text focuses on C-myc. The deregulation of C-myc transcription by retroviral insertion, chromosome translocation or gene amplification is a consistent oncogenic "mutation" in many forms of B-cell neoplasia.

C-myc like several other genes involved in neoplasia is implicated in multiple aspects of cellular life.

No single defined action has yet been established for myc.

Research has been concentrated on defining the important functions and assigning these to various differentiation lineages.

This book presents some perspectives on this complex problem.