Antibacterial Activity Study of Polyester Amides

The main aim of this research is to synthesize a new class of

multifunctional poly(ester amides) (PEAs), characterize them and to study their

structure-property relationship. These PEAs were synthesized by direct

polycondensation of 2,5-pyridine dicarboxylic acid with various diols and three other

varying diamines using diphenylphosphoryl chloride (DPPC) as the condensation

agent in pyridine solution. In order to study the effect of the thermal stability and

optical property, monomers of different molecular structures were used. The present

investigation also focuses on the study of anti-bacterial, anti-cancer activities and

wound healing capacity of the synthesized PEAs. Moreover nanofibers formed by

using electrospinning technique with blends of PEAs in PVC matrix were studied for

assessing the applicability of PEAs as nanofibers. This chapter highlights literature on

the role of various synthetic PEAs which result from the several combinations of

monomers in order to design materials with desirable properties for several

applications in various fields.