He's one small mouse on one very big adventure: Stuart Little is not ordinary mouse. Born to a family of humans, he lives in New York City with his older brother George and Snowball the cat. Though he's shy and thoughtful, he's also a true lover of adventure.

Stuart's greatest adventure comes when his best friend, a beautiful little bird named Margalo, disappears from her nest. Determined to track her down, Stuart ventures away from home for the first time in his life. He finds adventure aplenty. But will he find his friend?

Stuart Little is a 1945 American children's novel by E. B. White, his first book for children, and is widely recognized as a classic in children's literature. Stuart Little was illustrated by the subsequently award-winning artist Garth Williams, also his first work for children. It is a realistic fantasy about a mouse-like human boy named Stuart Little. According to the first chapter, he ″looked very much like a rat/mouse in every way″.