Therapeutic Oligonucleotides : Antisense, Rnai, Triple Helix, Enhancer-Decoy, Cpg and DNA Chips

This work is concerned with various aspects of oligonucleotides including triplex DNA, transcription factor decoy, antisense DNA/RNA, ribozymes, PNA, 2',5'-oligoadenylates, RNAi, and CpG immune-stimulating oligomers, diagnostic oligonucleotide chips (DNA chips), and gene therapy vectors.

These oligonucleotides can modulate gene-specific expression within cells and can identify genes involved in diseases.

Recent developments in oligonucleotide research have demonstrated the potential utility of oligonucleotides as therapeutic agents, particularly in the treatment of cancer, AIDS and other diseases.