Biomarkers in Drug Development : A Handbook of Practice, Application, and Strategy

By focusing on how to identify, develop, and integrate biomarkers into drug development, this book will improve biomarker use and enhance pharmaceutical decision making.

The coverage includes case studies showing how biomarkers can substantively impact drug development timelines and costs, enable better compound selection and reduce late stage attrition, and facilitate personalized medicine.

It describes biomarker technologies, characterization and validation, and applications including in discovery, preclinical safety assessment, clinical trials, and translational medicine.

The text, a useful resource for the pharmaceutical industry, also looks at practical issues and intellectual property concerns.