Biometals in neurodegenerative diseases: mechanisms and therapeutics

Biological metals (biometals) have key functions in the brain but can also induce degenerative changes due to abnormalities in homeostatic mechanisms. The scientific literature in this field is advancing rapidly with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and others. Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics. Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in the brain function, disease and as therapeutic targets. Chapters cover metals in Alzheimer's Disease, Parkinson's Disease, Motor Neuron Disease, Autism, and lysosomal storage disorders. This book is written for academic researchers, clinicians, and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, and neurology

*Authoritative and timely resource bringing together the major findings in the field for those with an interest in metals and their role in the brain function, disease and as therapeutic targets.

*Written for academic researchers, clinicians, and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, and neurology

*Edited by international leaders in the field who have contributed greatly to the study of metals in neurodegenerative diseases