A mathematical approach to multilevel, multiscale health interventions: pharmaceutical industry decline and policy response

This book examines the 30-year collapse of pharmaceutical industry productivity in the search for small molecule 'magic bullet' interventions.

The relentless escalation of inflation-adjusted cost per approved medicine in the US has driven industry giants to, at best, slavish imitation in drug design, and at worst, to the abandonment of research and the embracing of widespread fraud in consumer marketing.

This book adapts formalism across a number of disciplines to the strategy for design of mutilevel interventions.